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Team leader Hiroshi Ito
the clinical study about pathologic condition and therapy evaluation of brain function, mental disease and neurologic disorder.
Team leader Makoto Higuchi
basic research of the molecular mechanism on the mental and neurological disorders using model animals.
Team leader Tetsuya Suhara
translational research of the molecular mechanism organizing the cognitive systems and the localization of brain function.
Schizophrenia is a mental disorder, with the main symptoms involving delusion, hallucination, inferential thinking and negative symptoms.
Mood Disorder is a mental disorder that has disturbance in mood or emotion as a main symptom, and it causes depressive episodes. Bipolar Disorder is characterized by the repetition of depressive and manic episodes.
Alzheimer's disease is characterized by the dementia and pathology defined by the presence of hallmark lesions in the brain. The disease may have large impacts on the societies with growing elderly population.
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Most drugs used for mentalDisorders function by bindingto receptors of neurotransmit-ters in brain and blocking orreinforcing their signal tranmission.
Among neural networks,dopamine neural activation in the cerebral cortex is especially considered to play an important role in cognition, reward and memory.
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