Introduction

Our research focuses on the neural processes of controlling motivation and emotions. We study motivational- and emotional-related brain signals in normal as well as model animals, using multidimensional methods, such as PET, MRI, and neuronal recordings. Through the corporation with clinical studies, our research will contribute to diagnosis and treatment for the psychiatric disorders that caused by motivational or emotional dysfunctions.

Research Introduction

1. Brain mechanism of controlling motivation and emotion

To identify the neural network and processing involving in controlling motivation and emotion, we are applying to the multidisciplinary approach, including PET measurements, neuronal recordings, and the assessment of behavior in animals. We are also attempting to elucidate the molecular mechanism behind the decreasing motivation in depression model animals.

2. Developing animal models and behavioral assessments

We are developing monkey model of developmental disorders. We also develop assessment methods with taking advantage of monkey behaviors extrapolated from the symptoms. Combine with in vivo imaging technics, the models and assessments allow us to identify the specific dysfunctions and underlying molecular mechanism in developmental disorders.

3. Imaging biomarkers for psychiatric and neurodegenerative disorders

Applying PET biomarkers in human studies to animal models, we attempt to understand the mechanism of symptoms. We are also aiming to establish new biomarkers originated from our findings of animal models studies.

members