6.1

PUBLICATIONS


>> Annual Report 2002-2003

The list includes publications by the staff members issued during
the period from April 1, 1997 to March 31, 1998

Division of Education and Sientific Services
Oros, J., Fernandez. A., Rodriguez, J. L., Franklin, C. L., Matsushita, S.and Poveda, J. B: Association of cilia-associated respiratory (CAR) bacillus with natural chronic tracheitis in goats. J. Comp. Path., 117, 289-294, 1997.

Okamoto, M. and Matsumoto, T.: Production of germfree mice by embryo transfer. Germfree Life and its Ramifications. Hashimoto, K., Sakakibara, B., Tazume, S. and Shimizu, K. eds., XII ISG Publishing Committee, 21-24, 1996.

Nakagata, N., Okamoto, M., Ueda, O. and Suzuki, H.: Positive effect of partial zona-pellucida dissection on the in vitro fertilizing capacity of cryo-preserved C57BL/6J transgenic mouse spermatozoa of low motility.
Biol. Reprod., 57, 1050-1055, 1997.

Aoki, K., Okamoto, M., Tatsumi, K. and lshikawa, Y.: Cryopreservation of medaka spermatozoa. Zoological Science , 14, 641-644, 1997.

Okamoto, M.,Nakagata, N., Ueda, O., Kamada, N. and Suzuki, H.: Cryopreservation of gene disrupted mice spermatozoa. J. Mamm. Ova Res., 15, 77-80, 1998.


Division of Radiation Research
Tomitani, T.: Analysis of potential distribution in a gaseous counter of rectangular cross-section, Selected papers on Photon-Counting Detectors, SPIE Milestone Series, Vol. MS 143, pp31-43, 1997. Elsevier, Amsterdam. Reproduction of Nucl. Instr. & Meth. Vol. 100, pp. 179-191, 1972.

Yamamoto, M.,Yasuda N, Kaizuka *1, Yamagishi M*2, Kanai T, Ishigure N, Furukawa A, Kurano M, Miyahara N, Nakazawa M*1, Doke T*3, Ogura K*4: Cr-39 sensitivity analysis on heavy ion beam with atomic force microscope. Rad Meas, 28: 227-230, 1997 (*1Quantum Engin. and Systems Sci., Univ. of Tokyo, *2Physics,Toho Univ. *3Waseda Univ. *4Coll. Ind. Tech., Nihon Univ.)

Shiragai, A., Saitou, M.,* Kudo, I.,** Kanaiwa-Kudo, S.,*** Matsumoto, T., Furuse, T., Yanai, T.,* Ichinohe, K.,* Sato, F.,* and Ohmomo, Y.*: Estimation of the Absorbed Dose to mice in prolonged Irradiation by Low Dose Rate ¦Ã-Rays from 137Cs Sources. Radioisotopes 46, 904-911, 1997
(*Institute for Environmental Sciences, **Nuclear Fuel Environment Co., Ltd., ***Tohoku Nuclear Co., Ltd.)


Division of Biology and Oncology
Sakiyama, H., Nakagawa, K., Kuriiwa, K., Imai, K., Okada, Y., Tsuchida, T., Moriya, H. and Imajoho-Ohmi, S: Cell Yissue Res., 288, 557-565, 1997.

Fushiki, S., Hyodo-Taguchi, Y., kinoshita, C., Ishikawa, Y. and Hirobe, T.: Short-and long-term effects of low-dose prenatal X-irradiation in mouse cerebral cortex, with special reference to neuronal migration. Acta Neuropathol., 93, 443-449, 1997.

Hyodo-Taguchi, Y., Fushiki, S., kinoshita, C., Ishikawa, Y. and Hirobe, T.: Effects of continuous low-dose prenatal irradiation on neuronal migration in mouse cerebral cortex. J. Radiat. Res. 38, 87-94, 1997.

Kamisaku, H., Aizawa, S., Kitagawa, M., Ikarashi, Y. and Sado, T.: Limiting dilution analysis of T-cellprogenitors in the bone marrow of thymic lymphoma-susceptible B10 and resistant C3H mice after fractionated whole-body X-irradiation, Int. J. Radiat. Biol. 72, 191-199, 1997

Nakagawa, K., Sakiyama, H., Fukazawa, T., Matsumoto, M., Takigawa, M., Toyoguchi, T., Moriya, H.: Coordinated change between complement Cls producion and chondrocyte differentiation in vitro, Cell Tissue Res., 289, 299-305, 1997

Ichimura, S., Mita, K. and Sugaya, K.: A major non-LTR retrotransposon of Bombyx mori, L1Bm., J. Mol. Evol., 45, 253-264, 1997

Akira Fujimori, Ryoko Araki, Ryutaro Fukumura, Toshiyuki Saito, Masahiko Mori, Kazuei Mita, Kouichi Tatsumi, Masumi Abe: The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb. Genomics, 45, 194-199, 1997

Shuji Ohzeki, Akira Tachibana, Kouichi Tatsumi and Takesi Kato: Spectra of spontaneous mutations at the hart locus in colorectal carcinoma cell lines defective in mismatch repair, Cancinogenesis, 18(6), 1127-1133, 1997

Ishikawa, Y. and Hyodo-Taguchi, Y.: Heritable malformation in the progeny of the male medaka (Oryzias latipes) irradiated with X-rays. Mutation Res., 389, 149-155, 1997

Aoki, K., Okamoto, M., Tatsumi, K. and Ishikawa, Y.: Cryopreservaiton of medaka spermatozoa. Zool. Sci., 14, 641-644, 1997

Zama, M.: Translational pauses during the synthesis of proteins and mRNA structure. Nucleic Acids Res. Symp. Ser., 37, 179-180, 1997

Kawai, H., Kitamura, Y., Nikaido, O., Tatsuka, M., Hama-Inaba., Muto, M., Ohyama, H., Suzuki, F.: Isolation and characterization of apoptosis-resistant mutants from a radiosensitive mouse lyphoma cell line. Radiat. Res., 149, 41-51, 1997

Hirobe, T., Wakamatsu, K.* and Ito, S.*: Effects of genic substitution at the agouti, brown, albino, dilute, and pink-eyed dilution loci on the proliferation and differentiation of mouse epidermal melanocytes in serum-free culture. Eur. J. Cell Biol., 75, 184-191, 1998 *Fujita Health University, Chemistry.

Hyodo-Taguchi, Y., Fushiki, S., Kinoshita, C., Ishikawa, Y. and Hirobe, T.: Effects of low-dose X-irradiation on the development of the mouse cerebellar cortex. J. Rad. Res ., 39, 11-19, 1998. *Kyoto Prefectural University, Neurological Diseases and Geriatrics.

Nenoi, M., Mita, K., Ichimura, S. and Kawano, A: Higher frequency of concerted evolutionary events in rodents than in man at the polyubiquitin gene VNTR locus. Genetics, 148, 867-876, 1998

Ichimura, S., Hamana, K. and Nenoi, M.: Significant increases in the steady stated of putrescine and spermidine/spermine-N1-acetyltransferase mRNA in HeLa cells accompanied by growth arrest, Biochem Biophys Res Commun, 243, 518-521, 1998

Takahashi, A.*, Yano, T.*, Matsumoto, H.*, Wang, X.*, Ohnishi, K.*, Tamamoto, T.*, Tsuji, K.*, Yukawa, O. and Ohnishi, T.*: Effects of accelerated carbon-ions on growth inhibition of transplantable human esophageal cancer in nude mice, Cancer Letters, 122, 181-186, 1998
*Departments of Biology, Surgery and Oncoradiology, Nara Medical University.

Ohnishi, T.*, Takahashi, A.*, Yano, T.*, Matsumoto, H.*, Wang, X.*, Ohnishi, K.*, Tamamoto, T.*, Tsuji, K.*, Furusawa, Y. and Yukawa, O.: Hyperthemic enhancement of tumour growth inhibitinob by accelerated carbon-ions in transplantable human esophageal cancer, Int. J. Hyperthmia, 14, 195-202, 1998
*Departments of Biology, Surgery and Oncoradiology, Nara Medical University.


Division of Radiobiology and Biodosimetry
Radiation effects on embryos of preimplatation. Wang, B. and Zhou, X.: Chinese Journal of Radiation Medicine and Protection, 17(6): 455-477, 1997.

Apoptosis induction in cultured mouse embryonic mid brain cells. Wang, B., Fujita, K., Watanabe, K., Mitani, H., Yamada, T. and Shima, A.: Radiat. Res. 147; 304-308. 1997.

Eguchi-Kasai, K., Murakami, M., Itsukaichi, H., Fukutsu, K., Yatagai, F., Kanai, T., Ohara, H. and Sato, K.: Repair of DNA double-strand breaks and cell killing by charged particles. Adv. in Space Res., 22(4): 543-549, 1998.

Fukumura, R., Araki, R., Fujimori, A., Mori, M., Saito, T., Watanabe, F., Sarashi, M., Itsukaichi, H., Eguchi-Kasai, K., Sato, K., Tatsumi, K. and Abe, M.: Leucine to proline substitution (3191) in DNA-PKcs affects the signal joint formation as well as coding joint formation of V(D)J recombination. J. Biol. Chem., 273, 13058-13064, 1998.

Kanda, R., Kobayashi, S. and Kanda, J.: Risk perception on industrial and social events among students of general education course in a Japanese University Japanese Journal of Risk Analysis, 8(2), 128-134, 1997.
(*Shizuoka University)

Kusumoto, S.*, Jinnai, I.*, Matsuda, A.*, Murohashi, I.*, Bessho, M.*, Saito, M.*, Hirashima, K.*, Heshiki, A.* and Minamihisamatsu, M.: Bone marrow patterns in patients with aplastic anemia and myelodysplastic syndrome; observations with magnetic resonanece imaging. Eur. J. Haematol., 59, 155-161, 1997.
(*Saitama Medical Scool)

Fukushima, S.*1, Ozeki, S.*1, Tang, T. J.,*1, Koizumi, M.,*1 Matsumura, S.,*1 lnoue, T.,*1 Inoue, T.,*1 Yamazaki, H.,*2 Murayama, S.,*3 Hatanaka, K.,*1 Ejiri, H.,*1 and Kasai, K.: Induction of p53 protein by carbon-ion and proton beamirradiation in two close human lymphoblastoid cell lines with different p53 status. Oncology Reports, 4: 481-484, 1977.
*1Osaka University, *2DUniversity of Pennsylvania, *3Nat. Cancer Center Hospital


Division of Radiotoxicology and Protection
Oghiso, Y., Yamada, Y. and Iida, H.: High frequency of leukemic lymphomas with osteosarcomas but no myeloid leukemias in C3H mice after 239Pu citrate injection. J. Radiat. Res., 38, 77-86, 1997.

Yamada, Y., Koizumi, A. and Fukuda, S.: Aerosolization of a Chelating Agent, Ca-DTPA, for Emergent Inhalation Therapy. J. Health Phys., 32, 167-172, 1997.

Fukutsu, K., Kanai, T., Furusawa, Y. and Ando, K.: Response of mouse intestine after single and fractionated irradiation with accelerated carbon ions with a spread-out bragg peak. Radiation Research, 148, 168-174, 1997.

Fukuda, S., Iida, H., Yamada, Y., Koizumi, A. and Ishigure, N.: Effects of DTPA therapy on removal of inhaled high-fired plutonium oxide in rats. J. Health. Phys., 32 383-386, 1997.

Ogiso, Y., Yamada, Y., Iida, H. and Inaba, J.: Differential dose responses of pulmonary tumor types in the rat after inhalation of plutonium dioxide aerosols. J. Radiat. Res., 39 61-72, 1998.


Division of Human Environment
Epidemiological study group on evaluation of individual doses (Y. Yoshimoto et al) : Reliability of individual doses relating to the epidemiological studies on nuclear industry workers in Japan (1) (in Japanese) , RADIOISOTOPES, 46, 833-843, 1997

Epidemiological study group on evaluation of individual doses (Y. Yoshimoto et al) : Reliability of individual doses relating to the epidemiological studies on nuclear industry workers in Japan (2) (in Japanese) . RADIOISOTOPES, 46, 917-932, 1997

Fujimoto, K.: Correlation between Indoor Radon Concentration and Dose Rate in Air from Terrestrial Gamma Radiation in Japan. Health Physics 75, 1-7; 1998.

Fujimoto, K.: Correlation between Nationwide Indoor Radon and Terrestrial Gamma Survey Data in Japan. Proceeding of the 7th Tohwa University International Symposium, Radon and thoron in the human environment, Oct. 23-25, 1997.

Fujimoto, K., Kobayashi, S., Uchiyama, M., Doi, M. and Nakamura, Y.: Nationwide Indoor Radon Survey in Japan, Hoken Butsuri 32, 41-51, 1997.
5. Iimoto, T., Tokonami, S. and Kurosawa, R.: Radiat. Prot. Dosim., 72, 55-60, 1997.

Iimoto, T., Fujimoto, K., Tokonami, S. and Kurosawa, R.: Characteristics of Major Filters Used for 222Rn Progeny Measurements. Radiation Measurements, accepted. 1997.

Ishikawa, T. and Uchiyama, M.: Calculation of the counting efficiency for Cs-137 using voxel phantoms with lungs and a skeleton. Radiat. Prot. Dosim., 69; 199-204, 1997.

Ishikawa, T. and Uchiyama, M.: Estimation of the counting efficiency for individual subjects in Cs-137 whole-body counting, using voxel phantoms. Radiat. Prot. Dosim., 71; 195-200, 1997.

Kakuta, I., Yukawa, M., and Nishimura, Y.: Effect of water salinity on the trace elemental composition of Otoliths from Tridentiger obscurus. Bull. Soc. Sea Water Sci. Jpn. 51: 388-394,1997

Kawamura, H.: 2.2 Organ mass measurement, in "Compilation of anatomical, physiological and metabolic characteristics for a Reference Asian Man, Vol. 1, Data summary and conclusions," IAEA-TECDOC-1005 (1998) , 27-55.

Nishimura, Y., Watanabe, Y., M, H. Jia., Takeda, H., Wada, and M. Yukawa,M.: Intestinal absorption of 14C-Chitosan in Rats. Chitin and Chitosan Research, 3: 55-61, 1997.

Nishizawa K.: Dose estimation and risk-benefit analysis in mammography. Jpn. J. Med. Phys. Supplement 53; 17-32,1997

Sahoo, S. K. and Masuda, A.: Precise measurement of zirconium isotopes by thermal ionization mass spectrometry, Chem. Geol., 141, 117-126, 1997.

Shiraishi, K.: Sensitivity Comparison for electron spin resonance (ESR) on carbohydrates as dosimeter materials. Adv. ESR Appl., 13, 4-10, 1997.

Shiraishi, K., Tagami, K., Ban-nai, T., Yamamoto, M., Muramatsu, Y., Los, I. P., Phedosenko, G. V., Korzun, V. N., Tsigankov, N. Y., and Segeda, I. I.: Daily intakes of 134Cs, 137Cs, 40K, 232Th, and 238U in Ukrainian males. Health Physics, 73, 807-812, 1997.

Tanaka, G., Kawamura, H. and Shiraishi, K: Physical, and anatomical data, and part of physiological and metabolic data for normal Japanese with special reference to establishing Reference Asian Man model for the anatomical characteristics, in "Compilation of anatomical, physiological and metabolic characteristics for a Reference Asian Man, Vol. 2, Country reports," IAEA-TECDOC-1005 (1998) , 95-112.

Tokonami, S., Takahashi, F., Iimoto, T. and Kurosawa, R.: Health Phys., 73, 494-497, 1997.
7. Matsusaka, N., Yamakawa, Y., Sato, I., Tsuda, S., Kobayashi, H., Nishimura, Y.: Organ distribution of 137Cs in mice fetuses and their dams. Radioisotopes, 46: 219-225,1997.

Wada, M., Nishimura, Y., Watanabe, Y., Takita, T., and Innami, S.: Chitosan intake accelerates urinary calsium excretion in rats. Biosci. Biotech. Biochem., 6: 1206-1208, 1997.

Watanabe, Y., Nakamura, Y., and Ishii R.: Relationship between Starch Accumulation and Activities of the Related Enzymes in the Leaf Sheath as a Temporary Sink Organ in Rice Plant (Oryza sativa L.) . Australian Journal of Plant Physiology, 24: 563-569, 1997.

Yamamoto, M., Kofuji, H., Shiraishi, K., and Igarashi, Y.: An attemp to evaluate dry deposition velocity of airbore 816D816C8175Pb in a forest ecosystem. J. Radioanal. Nuc. Chem. Art., 227, 81-87,1998.

Yoshimoto, Y. and Yoshinaga, S.: Significance and limits of mortality survey in the vicinity of nuclear power stations as a monitoring (in Japanese) . Proceedings of the Japan Radiation Research Society, the 40th annual meeting,88,1997.

Yoshinaga,S. Aoyama,T. and Yoshimoto,Y.: Significance and limitations of a cohort study of radiological technologists in Japan (in Japanese) . Journal of Epidemiology, 148, 7 , 1997.

Yukawa, M., Watanabe,Y., Nishimura, Y., Shiraishi, K., Kawamura, H., and Sakurai, S: Application of PIXE, NAA and ICP techniques to the determination of trace elements in food and diet samples. IAEA-SM-344/2: 435-446,1977.

Yukawa,M.: Proceedings of 34th Seminar on Science and Technology. Small Accelerators and Their Application: 151-161,1997.

Yukawa, M., Watanabe, Y., Nishimura, Y., Shiraishi, K., Kawamura, H., and Sakurai,S.: Proceedings of International Symposium on Harmonization of Health Related Environmental Measurements Using Nuclear and Isotopic Techniques: 435-446,1997.

Yukawa, M., Kimura, A., Watanabe, Y., and Sakurai, S.: Distribution of elements in beansprout determined by PIXE analysis. Int. J. PIXE, 5: 69-77,1995.

Yukawa, M., Watanabe, Y., and Nishimura, Y.: Application of PIXE technique to determination of trace elements in diet and comparison with NAA and ICP-AES. Int. J. PIXE. 6: 395-403,1996.

Yukawa, M., Watanabe, Y., and Nishimura, Y.: Determination of trace elements in mate using PIXE analysis. Int. J. PIXE. 6: 505-509,1996.


Division of Radiation Health
Taki, S., T. Saito, K. Ogasawara, T. Fukuda, M. Sato, S. Hida, G. Suzuki, M. Mitsuyama, E.H.Shin, S. Kojima, T. Taniguchi, and Y. Asano: Multistage regulation of Thl-type immune responses by the transcription factor IRF-1. Immunity 6: 673-679, 1997

Hachiya, M., shimizu, S., Osawa, Y. and Akashi, M: Endogenous production of tumour necrosis factor is required for manganese superoxide dismutase expression by irradiation in the human monocytic cell line THP-1. Biochem. J 328, 615-623, 1997


Bioregulation Research Group
Onoda, M. and Inano, H.: Distribution of casein-like proteins in various organs of rat, J. Histochem. Cytochem., 45: 663-674, 1997

Furuse, M., Tsuneoka, K., Uchida, K*., and Nomoto, K*.: J. Rediat. Res., 38, 111-120, 1997. (*Yakult Central Institute for Microbiological Research)

Susa, N.*, Ueno, S.*, Furukawa, Y.*, Ueda, J., and Sugiyama, M.**: Potent protective effcct of melatonin on chromium (VI) -induced DNA single-strand breaks, cytotoxicity, and lipid pcroxidation in primary cultures of rat hepatocytes, Toxicol. Applied Pharmacol., 144 377-384, 1997. (*Kitazato Univ., **Asunaro Pharmacy)

Ueda, J., Hanaki, A.*, Yoshida, N.** and Nakajima, T.***: Proton nuclear magnetic resonance studies of the complexation of Zn (II) with histidine-containing peptides, L-histidylA059L-histidylglycylglycine and LA059histidylglycyl-LA059histidylgycine, Chem. Pharm. Bull., 45, 1108-1113, 1997. (*Shizuoka Univ., **Tokyo Med. Dent. Univ., ***Suntory Inst. for Bioorg. Res.)

Noda, Y.*, Anzai, K., Mori A.*, Kohno, M.**, Shinmei, **, Packer, L.*: Hydroxyl and superoxide anion radical scavenging activities of natural source antioxidants using the computerized JES-FR30 ESR spectrometer system. Biochem Mol. Biol. Internat., 42, 35-44-1997.
(*University of California, **JEOL)

Lee, S.*, Kiyota, T.*, Kunitake, T.*, Matsumoto, E.*, Yamashita, S.**, Anzai, K., Sugihara, G*: De Novo Design, Synthesis, and Characterization of a Pore Forming Small Globular Protein and Its Insertion into Lipid Bilayers. Biochemistry, 36, 3782-3791, 1997.
(*Fukuoka University, **Kyushu Universtity)

Miura, Y., Anzai, K., Urano, S. *, Ozawa, T.: In vivo Electron Paramagnetic Resonance Studies on Oxidative Stress Caused by X-Irradiation in Whole Mice. Free Rad. Biol. Med.., 23, 533-540, 1997.
(*Tokyo Metropolitan Institute of Gerontology)

Matsuzaki, K.*, Yoneyama, S.*, Fujii, N.*, Miyajima, K.*, Yamada, K.**, Kirino, Y.***, Anzai, K.: Membrane permeabilization mechanisms of a cyclic antimicrobial peptide, tachyplesin I, and its linear analog. Biochemistry, 36, 9799-9806, 1997.
(*Kyoto University, **Kyushu University, ***Tokyo University)

Inano, H., Suzuki, K., Onoda, M., and Wakabayashi, K*.: Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats. Carcinogenesis, 18, 1723-1727, 1997. (Gunma University)

Suzuki, K. T.*, Rui, M.*, Ueda J. and Ozawa, T.: Production of ascorbate and hydroxyl radicals in the liver of LEC rats in relation to hepatitis. Res. Commun. Molec. Pathol. Pharmacol ., 96, 137-146, 1997. (*Chiba Univ.)

Miura, Y., Anzai, K., Takahashi, S. and Ozawa, T.: A novel lipophilic spin probe for the measuremect of radiation damage in mouse brain using in vivo electron spin resonance (ESR) . FEBS Lett., 419, 99-102, 1997

N. Ikota, J. Hirano, R. Gamage, H. Nakagawa, and H. HamaA059Inaba, Improved Synthesis of 1-Deoxynojirimycin and Facile Synthesis of Its Stereoisomers from (S) -Pyroglutamic acid Derivative. Heterocycles, 46, 673-643 (1997).

Ishihara, H., & Tanaka, I.: Detection and cloning of unique integration sites of retrotransposon, intracisternal A-particle element in the genome of acute myeloid leukemia cells in mice. FEBS Letters, 418, (1997) 205-209.

Kawai H:*, Kitamura, Y.**, Nikaido, O.**, Tatsuka, M.*, Hama-Inaba, H., Muto, M., Ohyama, H. and Suzuki, F.*: Isolation and Characterization of Apoptosis-resistant Mutants from a Radiosensitive Mouse Lymphoma Cell Line. Radiat. Res., 149, 41-51, 1998.
(*Hiroshima University **Kanazawa University)

Hama-Inaba, H., Wang, B., Mori, M., Matsushima, T., Saitoh, T., Takusagawa, M., Yamada, T., Muto, M. and Ohyama, H.: Radiosensitive murine thymoma cell line 3SB. Characterization of its apoptosis-resistant variants induced by repeated X-irradiation. Mutation Res. 403, 85-94, 1998.


Genome Research Group
*1Zhao, J., *1Dynlacht, B., Imai, T., Hori, T., *1Harlow, E.: Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes Sphase entry. Genes and Development 1998 Genes & Dev. 12, 456-461, 1998.(*1Masachusetts Gen. Hosp.)

Saito, T., Seki, N., Yamauchi, M., Tsuji, S., Hayashi, A., Kozuma, S., Hori, T.: Structure, chromosomal location, and expression profile fo EXTR1 and EXTR2, new members of the multiple exostoses gene family. Biochemical and Biophysical Research Communications, 243: 61-66, 1998.

Hori, T., Seki, N., Ohira, M., Saito, T., Yamauchi, M., Sagara, M., Hayashi, A., Tsuji, S., Ito, H., Imai, T.: A distamycin A-inducible fragile site, FRA8E, located in the region of the hereditary multiple exostoses gene, is not involved in HPV16 DNA integration and amplification. Cancer Genetics and Cytogenetics, 101: 24-34, 1998.

Krien, M., S. Bugg, M. Palatsides, G. Asouline, M. Morimyo, and M. Connell, A NIMA homologue promotes chromatin condensation in fission yeast. J. Cell Sci., 1998. 111(7): p. 967-976.

*1Kawana, Y., *1Komiya, A., *1Ueda, T., *1Nihei, N., *1Kuramochi, H., *1Suzuki, H., *2Yatani, R., Imai, T., *3Dong, J-T., *4Imai, T., *4Yoshie, O., *5Barett, J. C., *5Isaacs, J. T., *1Shimazaki, J., *1Ito, H., *7Ichikawa, T.: Location of KAIl on the short arm of human chromosome 11 and frequency of allelicloss in advanced human prostate cancer. The prostate 32, 205-213, 1997.(*1Chiba Univ. School of Med, *2Fac. of Med, Mie Univ., *3Univ. of Virginia, *4Shionogi Inst. of Med. sci., *5Johns hopkins Univ. School of Med, *7Teikyo Univ. School of Med.)

*1Kitayama, E., *1Hosoda, F., *1Fukushima, M., *2Asakawa, S., *2Shimizu, N., Imai, T., *3Soeda, E., and *1Ohki, M.: A 3-Mbsequence ready contig map encompassing the multiple disease gene cluster on human chromosome 11 q13. 3. DNA Research, 4,281-289, 1997.(*1Radiol. Natl. Cancer Cntr Res. Inst, *2Keio Univ. Med., *3RIKEN Gene Bank)

Sugaya, K., Ajimura, M., Tsuji, H., Morimyo, M., Mita, K.: Alteration of the largest subunit of RNA polymerase II and its effect on chromosome stability in Schizosaccharomyces pombe. Mol. Gem. Genet., 258, 279-287, 1998.

Sugaya, K., Sasanuma, S., Nohata, J., Kimura, T., Hongo, E., Higashi, T., Morimyo, M., Tsuji, H., Mita, K.: Cloning and sequencing for the largest subunit of chinese hamster RNA polymerase II gene: identification of a muration related to abnormal induction of sister chromatid exchanges. Gene 194, 267-272, 1997.


Space and Particle Radiation Science Research Group
H. Yamaguchi: Calculation of G-value of Fricke Dosimeter irradiated by photons 100 eV-10 MeV, "Microdosimetry-An Interdisciplinary Approach-", Eds. by D. T. Goodhead, P. O'Neill and H. G. Menzel, PP. 97-100, The Royal Society of Chemistry 1997.

Suzuki, M., Kase, Y., Kanai, T., Yatagai, F. and Watanabe, M.: LET dependence of cell death and chromatin-break induction in normal human cells irradiated by neon-ion beams. International Journal of Radiation Biology, , 497-503, (1997).

Fukuda, S, Iida, H., Yamada, Y., Koizumi, A and Ishigure, H: Effects of DTPA therapy on removal of inhaled pultonium oxide in rats. J. Health Physics, 32 383-386, 1997.


Environment and Toxicological Sciences Research Group
Kubota, Y., Takahashi, S. and Sato, H.: Int. J. Radiat. Biol., 72, 71-78, 1997

Ban-nai, T., Muramatsu, Y. and Yoshida, S.: Health Physics, 72, 384-389, 1997

Uchida, S. and Tagami, K.: Separation and concentration of technetium using a Tc-selective extraction chromatographic resin. J. Radioanal. Nucl. Chem., 221, 35-39, 1997

Uchida, S. and Tagami, K.: Improvement of Tc Separation Procedure using a Chromatographic Resin for Direct Measurement by ICP-MS. Analytica Chimica Acta, 357, 1-3, 1997.

Ban-nai, T., Muramatsu, Y., Yoshida, S., Uchida, S., Shibata, S., Ambe, S., Ambe, F. and Suzuki, A.: Multitracer studies on the accumulation of radionuclides in mushrooms. J. Radiation Research, 38, 213-218, 1997

Kunst, F.*1, Fuma, S. et al.: The complete genome sequence of the Gram-positive bacterium Bacillus subtilis. Nature, 390, 249-256, 1997. *1Institut Pasteur, France

Yanagisawa. K. and Muramatsu, Y.: Transfer of Technetium from Soil to Plant. Russian Journal of Radiochemistry, 39, 375-378, 1997

Yanagisawa. K., Muramatsu, Y. and Ban-nai T.: Behavior of Technetium in Paddy Soils. Journal of Radioanalytical and Nuclear Chemistry, 226, 221-223 (1997)

Sun, Xue Zhi, Inoue, M., Yamamura, H. and Fukui, Y.: Effects of prenatal treatment with tritiated water on the developing brain in mice. International Journal of Radiation Biology 71(3): 309-313, 1977

Sun, Xue Zhi, Inoue, M., Fukui, Y., Muramatsu, H., Muramatsu, T. and Yamamura, H.: Effects of different fixatived on immunohistochemical demonstration of midkine using quick-frozen mouse embryonic brains. Environmetnal Medicine. 41(2): 104-106 (1977)

Takahashi, S., Kubota, Y. and Sato. H.: Mutant Frequencies in lacZ Transgenic Mice following the internal Irradiation from 89Sr or the External ¦Ã-Ray Irradiation. J. Radiat. Res., 39,53-60, 1998

Yoshida, S. and Muramatsu, Y.: Determination of major and trace elements in mushroom, plant and soil samples collected from japanese forests. Intern. J. Environ. Anal. Chem. 67, 49-58, 1997.

Sun, Xue Zhi, Inoue, M., Fukui, Y., Hisano, S., Sawada, K., Muramatsu, H. and Muramatsu, T.: An immunohistochemical study of radial glial cells in the mouse brain prenatally exposed to ¦Ã-irradiation. J. Neuropathology and Experimental Neurology 56(12), 1339-1348, 1997.


Low Dose Radiation Risk and Carcinogenesis Research Group
Kobayashi, S., Nishimura, M., Shimada, Y., Suzuki, F.*1, Matsuoka, A.*2, Sakamoto, H.*2, Hayashi, M.*2, Sofuni, T.*2, Sado, T., Ogiu, T.: Increased sensitivity of scid heterozygous mice to ionizing radiation. Int. J. Radiat. Res., 72, 537-545, 1997.(*1CHiroshima Univ., *2Natl. Inst. Health Sci. )

Kinebuchi, M.*, Matsuura, A.*, Ogiu, T., Kikuchi, K. *: Deviated overexpression of TCR-¦Â, TCR-¦Ã, CD-4, and CD-8 on thymic lymphomas induced by 1-propy1-1-nitrosourea. J. Immunol., 159, 748-756, 1997.(*Sapporo Med. Univ. )

Takahashi, T.*1, Yagi. T.*1, Kakinuma, S., Kurokawa, A.*1, Okada, T.*1, Aizawa, S.*2, Katagiri, T.*1: Supperession of autoimmune disease and of massive lymphadenopathy in MRL/Mp-lpr/lpr mice lacking tyrosine kinase fyn (p59fyn). J. Immunol., 159, 2532-2541, 1997.(*1Kitasato Inst., *2Kumamoto Univ. )

Sugaya, K., Sasanuma, S., Nohata, J., Kimura, T., Hongo, E., Higashi, T., Morimyo, M., Tsuji, H., Mita, K.: Cloning and sequencing for the largest subunit of Chinese hamster RNA polymerase II gene: identification of a mutation related to abnormal induction of sister chromatid exchanges. Gene,, 194, 267-272, 1997.

Nagasawa, M.*, Watanabe, F., Suwa, A.*, Yamamoto, K.*, Tsukada, K.*, Teraoka, H.*: Nuclear translocation of the catalytic component of DNA-dependent protein kinase upon growth stimulation in normal human T lymphocytes. Cell Struct. Funct. 22, 585-594, 1997.(*Tokyo Med. Dent. Univ. )

Chibazakura, T. *, Watanabe, F., Kitajima, S. *, Tsukada, K. *, Yasukochi, Y.*, Teraoka, H.*: Phosphorylation of human general transcription factors TATA-binding protein and transcription factors TATA-bindingprotein and transcription factor IIB by DNA-dependent protein kinase synergistic stimulation of RNA polymerase IIB by DNA-dependent protein kinase - synergistic stimulation of RNA polymerase II basal transcription in vitro. Eur. J. Biochem., 247, 1166-1173, 1997 (*Tokyo Med. Dent. Univ. )

Nishimura, A.*, Moriya, S.*, Ukai, H.*, Nagai, K.*, Wachi, M.*, Yamada, Y.*: Diadenosine 5', 5'''-Pl, P4-tetraphosphate (Ap4A) controls the timing of cell division in Escherichia coli. Genes Cells, 2, 401-413, 1997.(*Natl. Inst. Genet.)


Division of Accelerator Physics and Engineering
Net-lonization Cross Seetions of Rare Gases by Fully-stripped Heavy Ion impact: S. Makino, T. Matsuo, M. Mizutani. M. Sano, T. Kohno, T. Tonuma, H. Tawara, A. Kitagawa and T. Murakami; Phys. Seripta 73, (1997) 238-239.

Channeling with 290 MeV/u C6+Ions in a Si Crystal: T. Ito, T. Azuma, K. Komaki, Y. Yamazaki, T. Murakami, E. Takada, A. Kitagawa, M. Torikoshi and M. Sano; Phys. Seripta 73, (1997) 345-346.


Medical Physics and Engineering Office
Endo, M., Yoshida, K., Kamagata, N.,*1 Satoh, K.,*2 Okazaki, T.,*2 Hattori, Y.,*2 Kobayashi, S.,*2 Jimbo, M.,*2 Kusakabe, M.*2 and Tateno, Y.: Development of a 3D CT-scanner using a cone beam and video-fluoroscopic system. Radiation Medicine, 16, 7-12, 1998 (*1Univ. of Chiba, *2Sony Corp.)

Yoshida, K., Endo, M., Mori, K.,*1 Katada, K.,*2 Ueda, M.,*3 Toriwaki, J.*1 and Tateno, Y.: Virtualized angioscopy of the thoracic aorta in a rabbit model of atherosclerosis. Jpn. Circulation J., 62 198-200, 1998 (*1Univ. of Nagoya, *2Fujita Gakuen Univ., *3Osaka City Univ.)


Division of Radiation Medicine
Tsujii, H., Morita, S., Miyamoto, T., Mizoe, J., Mukai, M., Nakano, T., Kato, H., Kamada, T., Ishikawa, A. and Matsuoka, Y.: Preliminary results of phase I/II carbon-ion therapy at the national institute of radiological sciences. International Journal of Brachytherapy, 13(1), 1-8, 1997.

Yoshioka, H., Onaya, H., Itai, Y., Nishimura, H., Matsumura, A., Tsunoda, T., Kandatsu, S., Koga, M., Yoshikawa, K., Kato, H. and Tsujii, H.: Comparison between magnetization transfer contrast and fast spin-echo mr imaging of digenerative disease of the cervical spine at 0.3t. Magnetic Resonance Imaging, 15(1), 37-45, 1997.

Ohara, K., Okumura, T., Tsuji, H., Chiba, T., Min, M., Tatsuzaki, H., Tsujii, H., Akine, Y. and Itai, T.: Radiation tolerance of cirrhotic livers in relation to the preserved functional capacity: analysis of patients with hepatocellular carcinoma treated by focused proton beam radiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 38(2), 367-372, 1997.


Division of Accelerator Physics and Engineering
E. Urakabe. M. Inoue, Y. Iwashita. M. Kanazawa, T. Shirai, M. Torikoshi, M. Tadokoro, M. Nishi, A. Noda, K. Noda. S. Yamada, and Y. Fujita: Parallel Plate Ionization Chanber for Studying The Time Structure of Slow extracted Beam; Beam Science and Technology, Vol. 2, p. 23-29, 1997.

Sato, Y. and Soga, F.: Analysis of Relative Biological Effectiveness of High Energy Heavy lons in Comparison to Experimental Data, J. Radit. Res., 38, 103-110, 1997.

Diagnostic imaging by energetic radiactive particle beams Nuclear Physics a616 (1997) 478-489. AChatterjee, E. Takada, M. Torikoshi and M. Kanazawa


Division of Advanced Technology for Medical Imaging
Iyo, M., Namba, H., Fukushi, K., Shinotoh, H., Nagatsuka, S., Suhara., T., Sudo, Y., Suzuki, K. and Irie, T.: Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease.: lancet, 349, 1805-1809, 1997.

K. Andoh*1, K. Odagiri*1, T. Matsumoto*2, K. Yamashita*1, I. Ogino*1, T. Otsuka*1: Computed radiography excretory urography: Can the system sensitivity value be used as an image quality indicator?, J. Dig.Imag. 10(3), Aug., 1997: 132-136

Hasegawa, T*1., Murayama, H, Wada, Y.*2: Monte Carlo simulation of PET performance measurements for EXACT 47 at NIRS. Jpn. J. Med. Phys., 17 (72) , 83-93-1997.(*1Kitasato Univ., *2Siemens-Asahi Medical Technologies Ltd.

Ikehira H, Obata T, Koga M, Yoshida K. Human hepatic carbohydrate metabolism. Dynamic observation using 13C NMR without proton decoupling. Acta Radiologica. 1997; 38: 998-1002

Morio S, Oh H, Endo N, Kawano E, Nakamura H, Asai T, Saito y, Uchida Y, Ikehira H, Yoshida K. Magnetc resonance imaging of reticulo-endothelial system in patients with itiopathic thrombocytopenic purpura. Am J Hematol 1997; 56: 52-58

Furuya Y, Ikehira H, Obata T, Koga M, Yoshida K. The measurement of blood flow parameter with deuterium stable isotope MR imaging. Annals Nucl Med. 1997; 11: 281-284

Endo M, Yoshida K, Kamagata N, Satoh K, Okazaki T, Hattori Y, Kobayashi S, Jimbo M, Kusakabe M, tateno Y. Development of a 3D CT-scanner using a cone beam and videofluoroscopic system. Radiation Medicine 1998; 16: 7-12

Yoshida K, Endo M, Mori K, Katada K, Ueda M, Toriwaki J, Tateno Y. Virtualized angioscopy of the thoracic aorta in a rabbit model of atherosclerosis. Jpn Circ J 1998; 62: 198-200

Suhara T, Sudo Y, Yoshida K, Okubo Y, Fukuda H, Obata T, Yoshikawa K, Suzuki K, Sasaki Y. Lung as a reservoir for antideressants in pharmacokinetic drug interactions. Lancet 1998; 351: 332-335

Haradahira, T., Inoue, O., Kobayashi, K., and Suzuki, K.: Synthesis and Evaluation of Carbon-11 Labeled Non-peptide Antgonists for Cholecystokinin (CCK) Receptors:[11C]L-365, 260 and[11C]L-365, 346 Nucl. Med. Biol. 25, 230-208, 1998

Namba, H., Iyo, M., Shinotoh, H., Nagatsuka, S., Fukushi, K. and Irie, T.: preserved acetylcholinesterase activity in aged human cerebral cortex lancet, 352, 881-882, 1998

Namba, H. Iwadate, Y., Iyo, M., Fukushi, K., Irie., T., Sueyoshi, K., Tagawa, M. and Sakiyama., S.: Glucose and methionine uptake by rat brain tumor treated with produg-activated gene therapy Nucl. Med. Biol., 25, 247-250, 1998


Laboratory for Radioecology
Yamada, M.: 239-240Pu and 137Cs concentrations in salmon (Oncorhynchus keta) collected on the Pacific coast of Japan. J. Radioanal. Nucl. Chem., 223(1/2), 145-148, 1997.

Nozaki, Y.,*1, Zhang, J. and Amakawa, H.*1: The factionation between Y and Ho in the marine environment. Earth Planet. Sci. Lett., 148, 329-340, 1997.
(*1Tokyo University)

Miyazaki, T., Masuda, R.*1, Furuta, S.*2, and Tsukamoto, K. *1: Laboratory Observation on the Nocturnal Activity of Hatchery-reared juvenile Japanese Flounder, Fisheries Science, 63(2), 205-210, 1997.
(*1Tokyo Univ. O. R. I, *2Tottori Prefectural Government)

Yamada, M., and Nagaya, Y.: Temporal variations of 137Cs concentrations in the surface seawater and marine organisms collected from the Japanese coast during the 1980's. J. Radioanal. Nucl. Chem, 230(1/2), 111-114, 1988.




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